Analysis Note
ControlRat E18 cortex cells
Application
Research Sub CategoryNeurofilament & Neuron Metabolism
Research CategoryNeuroscience
Immunohistochemistry: Representive lot has been shown to work in adult mouse brain.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
Tubulin is one of several members of a small family of globular proteins which polymerize to form cytoskeletal structures called microtubules. The most common members of the tubulin family are α-tubulin and β-tubulin. Tubulin dimers, typically composed of α- and β-tubulin subunits, assemble onto microtubules forming large polymers. β-III tubulin is a unique microtubule subunit that is found expressed almost exclusively in neurons. Due to the unique expression pattern of β-III tubulin it is often utilized as a marker to identify neuronal cells from other brain cells such as glia which do not express it. β-III tubulin also serves as a cytoarchitectural marker since it is primarily found within neurite extensions.
Immunogen
Synthetic linear peptide corresponding to human Beta III Tubulin.
Legal Information
ALEXA FLUOR is a registered trademark of Life Technologies
Physical form
Affinity purified
Purified rabbit polyclonal conjugated to Alexa Fluor® 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA.
Quality
Evaluated by Immunocytochemistry in rat E18 cortex cells.
Immunocytochemistry Analysis: A 1:400 dilution of this antibody detected Beta III Tubulin in rat E18 cortex cells.
Specificity
This antibody recognizes Beta III Tubulin.
Storage and Stability
Stable for 1 year at 2-8°C from date of receipt.
Target description
50 kDa calculated
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