Anti-Beta III Tubulin; Alexa Fluor

Code: AB15708A4 D2-231

Analysis Note

ControlRat E18 cortex cells

Application

Research Sub CategoryNeurofilament & Neuron Metabolism

Research CategoryNeuroscience<...


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Analysis Note

ControlRat E18 cortex cells

Application

Research Sub CategoryNeurofilament & Neuron Metabolism

Research CategoryNeuroscience

Immunohistochemistry: Representive lot has been shown to work in adult mouse brain.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Tubulin is one of several members of a small family of globular proteins which polymerize to form cytoskeletal structures called microtubules. The most common members of the tubulin family are α-tubulin and β-tubulin. Tubulin dimers, typically composed of α- and β-tubulin subunits, assemble onto microtubules forming large polymers. β-III tubulin is a unique microtubule subunit that is found expressed almost exclusively in neurons. Due to the unique expression pattern of β-III tubulin it is often utilized as a marker to identify neuronal cells from other brain cells such as glia which do not express it. β-III tubulin also serves as a cytoarchitectural marker since it is primarily found within neurite extensions.

Immunogen

Synthetic linear peptide corresponding to human Beta III Tubulin.

Legal Information

ALEXA FLUOR is a registered trademark of Life Technologies

Physical form

Affinity purified

Purified rabbit polyclonal conjugated to Alexa Fluor® 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA.

Quality

Evaluated by Immunocytochemistry in rat E18 cortex cells.

Immunocytochemistry Analysis: A 1:400 dilution of this antibody detected Beta III Tubulin in rat E18 cortex cells.

Specificity

This antibody recognizes Beta III Tubulin.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Target description

50 kDa calculated

antibody formaffinity isolated antibody
antibody product typeprimary antibodies
biological sourcerabbit
clonepolyclonal
conjugateALEXA FLUOR® 488
Gene Informationhuman ... TUBB3(10381)mouse ... Tubb3(22152)rat ... Tubb3(246118)
NCBI accession no.NP_006077
Quality Level100
shipped inwet ice
species reactivity (predicted by homology)human (based on 100% sequence homology)
species reactivitymouse, rat
technique(s)immunocytochemistry: suitable, immunohistochemistry: suitable
UniProt accession no.Q13509
This product has met the following criteria to qualify for the following awards:



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